Article
DNA Methyltransferase Genes Are Associated with Oral Mucositis and Creatinine Levels in Oncopediatric Patients.
Genes - 24 May 2023
de Souza Beatriz Fernandes, Viana Filho José Maria Chagas, de Queiroz Neto José Nunes, Coêlho Marina de Castro, Valença Ana Maria Gondim, Persuhn Darlene Camati, de Oliveira Naila Francis Paulo
Abstract excerpt
The aim of this study was to investigate the association of single-nucleotide polymorphisms (SNPs) and the DNA methylation profiles of the DNA methyltransferase (DNMT) gene family with oral mucositis in children and adolescents with hematologic malignancies treated with methotrexate (MTX®). The population was comprised of healthy and oncopediatric patients aged between 4 and 19 years. An evaluation of oral...
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