Article
Genetic polymorphisms of genes involved in oxidative stress and inflammatory management in oncopediatric patients with chemo-induced oral mucositis.
Journal of applied oral science : revista FOB - 1 Jan 2022
Coêlho Marina Castro, Viana Filho José Maria Chagas, Souza Beatriz Fernandes de, Valença Ana Maria Gondim, Persuhn Darlene Camati, Oliveira Naila Francis Paulo de
Abstract excerpt
OBJECTIVE: Oral mucositis (OM) is a painful inflammatory oral condition that affects children who undergo chemotherapy. Oxidative stress is a known OM mediator and pro-inflammatory cytokines contribute to the amplification of the immune response. To investigate the possible associations of rs4880 (superoxide dismutase 2, SOD2 47 C/T), rs7943316 (catalase, CAT -21 A/T), rs1800629 (tumor necrosis factor α, TNF- α...
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