Polymorphism but not methylation status in the vitamin D receptor gene contributes to oral mucositis in children.

doi:10.1111/odi.14394

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Polymorphism but not methylation status in the vitamin D receptor gene contributes to oral mucositis in children.

Oral diseases - 1 Nov 2023

Viana Filho José Maria Chagas, de Souza Beatriz Fernandes, Coêlho Marina de Castro, Valença Ana Maria Gondim, Persuhn Darlene Camati, de Oliveira Naila Francis Paulo

Abstract excerpt

OBJECTIVE: To investigate the relationship between the polymorphisms rs1544410 (BsmI), rs2228570 (FokI) and rs731236 (TaqI) and DNA methylation status in the VDR gene (vitamin D receptor) with oral mucositis (OM) in oncopaediatric patients treated with methotrexate (MTX®). METHODS: The population comprised healthy patients with haematological malignancies aged between 5 and 19 years. An evaluation of oral...

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Adolescent

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

Receptors, Calcitriol

Young Adult

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Open in PubMed

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PMID: 36200993
DOI: 10.1111/odi.14394

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