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Article

Aligning germline and somatic mutations in prostate cancer. Are genetics changing practice?

BJU international - 1 Nov 2023

Cussenot Olivier, Cancel-Tassin Geraldine, Rao Srinivasa R, Woodcock Dan J, Lamb Alastair D, Mills Ian G, Hamdy Freddie C

Abstract excerpt

OBJECTIVE: To review the current status of germline and somatic (tumour) genetic testing for prostate cancer (PCa), and its relevance for clinical practice. METHODS: A narrative synthesis of various molecular profiles related to their clinical context was carried out. Current guidelines for genetic testing and its feasibility in clinical practice were analysed. We report the main identified genetic sequencing...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 37410655
DOI: 10.1111/bju.16120

Genes

AR
BRCA2
BRCA1
HOXB13
TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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