Article
Multi-site pre-therapeutic biopsies demonstrate genetic heterogeneity in patients with newly diagnosed diffuse large B-cell lymphoma.
Leukemia & lymphoma - 1 Sept 2023
Hersby Ditte Stampe, Schejbel Lone, Breinholt Marie Fredslund, Høgdall Estrid, Nørgaard Peter, Dencker Ditte, Nielsen Torsten Holm, Pedersen Lars Møller, Gang Anne Ortved
Abstract excerpt
Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous disease, both regarding clinical presentation, response to treatment and outcome. Recently, subclassification of DLBCL based on mutational profile has been suggested, and next generation sequencing (NGS) analysis may be relevant as part of the diagnostic workflow. This will, however, often be based on analysis of one tumor biopsy. Here, we present a...
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