Non-invasive monitoring of diffuse large B-cell lymphoma by cell-free DNA high-throughput targeted sequencing: analysis of a prospective cohort.

doi:10.1038/s41408-018-0111-6

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Article

Non-invasive monitoring of diffuse large B-cell lymphoma by cell-free DNA high-throughput targeted sequencing: analysis of a prospective cohort.

Blood cancer journal - 1 Aug 2018

Bohers Elodie, Viailly Pierre-Julien, Becker Stéphanie, Marchand Vinciane, Ruminy Philippe, Maingonnat Catherine, Bertrand Philippe, Etancelin Pascaline, Picquenot Jean-Michel, Camus Vincent, Menard Anne-Lise, Lemasle Emilie, Contentin Nathalie, Leprêtre Stéphane, Lenain Pascal, Stamatoullas Aspasia, Lanic Hélène, Libraire Julie, Vaudaux Sandrine, Pepin Louis-Ferdinand, Vera Pierre, Tilly Hervé, Jardin Fabrice

Abstract excerpt

From a liquid biopsy, cell-free DNA (cfDNA) can provide information regarding basal tumoral genetic patterns and changes upon treatment. In a prospective cohort of 30 diffuse large B-cell lymphomas (DLBCL), we determined the clinical relevance of cfDNA using targeted next-generation sequencing and its correlation with PET scan imaging at the time of diagnosis and during treatment. Using a dedicated DLBCL panel,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to DNA Copy Number Variations

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Identifiers

PMID: 30069017
DOI: 10.1038/s41408-018-0111-6
PMCID: PMC6070497

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