Article
Mutational heterogeneity in large B-cell lymphoma: insights from paired biopsies.
Annals of hematology - 1 Dec 2024
Hersby Ditte Stampe, Schejbel Lone, Breinholt Marie Fredslund, Høgdall Estrid, Nørgaard Peter, Nielsen Torsten Holm, Pedersen Lars Møller, Gang Anne Ortved
Abstract excerpt
INTRODUCTION: Large B-cell lymphoma (LBCL) exhibits striking clinical and molecular heterogeneity. New approaches have emerged to explore tumor heterogeneity and classify LBCL into biological categories. Consequently, the informational requirements from diagnostic samples to provide the necessary information have increased, but the adequacy of single-site biopsies to provide such information is largely unknown....
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