Article
Mannose binding lectin gene 2 (rs1800450) missense variant may contribute to development and severity of COVID-19 infection.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Apr 2021
Medetalibeyoglu Alpay, Bahat Gulistan, Senkal Naci, Kose Murat, Avci Kader, Sayin Gozde Yesil, Isoglu-Alkac Ummuhan, Tukek Tufan, Pehlivan Sacide
Abstract excerpt
BACKGROUND/OBJECTIVES: COVID-19 followed a mortal course in some young patients without any underlying factors, however, it followed a very benign course in some very older individuals with multiple comorbidities. These observations question if some genetic factors may be related to the vulnerability and poor prognosis of the disease. In this study, we aimed to investigate whether MBL2 gene B variant at codon 54...
Topics
- Adult
- Aged
- Aged, 80 and over
- COVID-19
- Case-Control Studies
- Comorbidity
- Female
- Genetic Predisposition to Disease
- Humans
- Male
- Mannose-Binding Lectin
- Middle Aged
- Mutation, Missense