Article
Evaluating significance of European-associated index SNPs in the East Asian population for 31 complex phenotypes.
BMC genomics - 13 Jun 2023
Qiao Jiahao, Wu Yuxuan, Zhang Shuo, Xu Yue, Zhang Jinhui, Zeng Ping, Wang Ting
Abstract excerpt
BACKGROUND: Genome-wide association studies (GWASs) have identified many single-nucleotide polymorphisms (SNPs) associated with complex phenotypes in the European (EUR) population; however, the extent to which EUR-associated SNPs can be generalized to other populations such as East Asian (EAS) is not clear. RESULTS: By leveraging summary statistics of 31 phenotypes in the EUR and EAS populations, we first...
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