Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Studying the Genetics of Complex Disease With Ancestry-Specific Human Phenotype Networks: The Case of Type 2 Diabetes in East Asian Populations.

Genetic epidemiology - 1 May 2016

Qiu Jingya, Moore Jason H, Darabos Christian

Abstract excerpt

Genome-wide association studies (GWAS) have led to the discovery of over 200 single nucleotide polymorphisms (SNPs) associated with type 2 diabetes mellitus (T2DM). Additionally, East Asians develop T2DM at a higher rate, younger age, and lower body mass index than their European ancestry counterparts. The reason behind this occurrence remains elusive. With comprehensive searches through the National Human Genome...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asia, Eastern
Share to Asian People
Share to Diabetes Mellitus, Type 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Models, Genetic

Share to Myocardial Infarction

Share to Odds Ratio

Share to Ovarian Neoplasms

Share to Schizophrenia

Source

Open in PubMed Open full text

Identifiers

PMID: 27061195
DOI: 10.1002/gepi.21964
PMCID: PMC5071667

Genes

HPN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Studying the Genetics of Complex Disease With Ancestry-Specific Human Phenotype Networks: The Case of Type 2 Diabetes in East Asian Populations.PMID 27061195Read ↗

Large-scale meta-analysis of over one million individuals reveals the genetic architecture of 127 complex traits in East Asian populationsSemantic proximity Read ↗

Multi-ancestry polygenic mechanisms of type 2 diabetes.Semantic proximity Read ↗

Ancestry-specific high-risk gene variant profiling unmasks diabetes-associated genes.Semantic proximity Read ↗

Trans-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translationSemantic proximity Read ↗

Multi-ancestry genome-wide study in >2.5 million individuals reveals heterogeneity in mechanistic pathways of type 2 diabetes and complicationsSemantic proximity Read ↗

The trans-ancestral genomic architecture of glycemic traits.Semantic proximity Read ↗

The PAGE Study: How Genetic Diversity Improves Our Understanding of the Architecture of Complex TraitsSemantic proximity Read ↗

Evolutionarily derived networks to inform disease pathways.Semantic proximity Read ↗

Polygenic risk score for type 2 diabetes shows context-dependent effects across populations.Semantic proximity Read ↗

Multi-ancestry Polygenic Mechanisms of Type 2 Diabetes Elucidate Disease Processes and Clinical HeterogeneitySemantic proximity Read ↗

Characterizing the polygenic architecture of complex traits in populations of East Asian and European descent.Semantic proximity Read ↗

Importance of Diversity in Precision Medicine: Generalizability of Genetic Associations Across Ancestry Groups Toward Better Identification of Disease Susceptibility Variants.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.