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Article

Multi-trait GWAS for diverse ancestries: mapping the knowledge gap.

BMC genomics - 17 Apr 2024

Troubat Lucie, Fettahoglu Deniz, Henches Léo, Aschard Hugues, Julienne Hanna

Abstract excerpt

BACKGROUND: Approximately 95% of samples analyzed in univariate genome-wide association studies (GWAS) are of European ancestry. This bias toward European ancestry populations in association screening also exists for other analyses and methods that are often developed and tested on European ancestry only. However, existing data in non-European populations, which are often of modest sample size, could benefit from...

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PMID: 38627641
DOI: 10.1186/s12864-024-10293-3
PMCID: PMC11022331

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