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Article

Dissecting shared genetic architecture between obesity and multiple sclerosis.

EBioMedicine - 1 Jul 2023

Zeng Ruijie, Jiang Rui, Huang Wentao, Wang Jiaxuan, Zhang Lijun, Ma Yuying, Wu Yanjun, Meng Meijun, Lan Hekui, Lian Qizhou, Leung Felix W, Sha Weihong, Chen Hao

Abstract excerpt

BACKGROUND: Observational studies have associated obesity with an increased risk of multiple sclerosis (MS). However, the role of genetic factors in their comorbidity remains largely unknown. Our study aimed to investigate the shared genetic architecture underlying obesity and MS. METHODS: By leveraging data from genome-wide association studies, we investigated the genetic correlation of body mass index (BMI) and...

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Share to Genetic Associations and Epidemiology
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Mendelian Randomization Analysis

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Share to Polymorphism, Single Nucleotide

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Source

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Identifiers

PMID: 37300932
DOI: 10.1016/j.ebiom.2023.104647
PMCID: PMC10363440

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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