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Article

Investigating the shared genetic architecture between multiple sclerosis and inflammatory bowel diseases.

Nature communications - 24 Sept 2021

Yang Yuanhao, Musco Hannah, Simpson-Yap Steve, Zhu Zhihong, Wang Ying, Lin Xin, Zhang Jiawei, Taylor Bruce, Gratten Jacob, Zhou Yuan

Abstract excerpt

An epidemiological association between multiple sclerosis (MS) and inflammatory bowel disease (IBD) is well established, but whether this reflects a shared genetic aetiology, and whether consistent genetic relationships exist between MS and the two predominant IBD subtypes, ulcerative colitis (UC) and Crohn's disease (CD), remains unclear. Here, we use large-scale genome-wide association study summary data to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34561436
DOI: 10.1038/s41467-021-25768-0
PMCID: PMC8463615

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