Article
Genetic overlap between multiple sclerosis and several cardiovascular disease risk factors.
Multiple sclerosis (Houndmills, Basingstoke, England) - 1 Dec 2016
Wang Yunpeng, Bos Steffan D, Harbo Hanne F, Thompson Wesley K, Schork Andrew J, Bettella Francesco, Witoelar Aree, Lie Benedicte A, Li Wen, McEvoy Linda K, Djurovic Srdjan, Desikan Rahul S, Dale Anders M, Andreassen Ole A
Abstract excerpt
BACKGROUND: Epidemiological findings suggest a relationship between multiple sclerosis (MS) and cardiovascular disease (CVD) risk factors, although the nature of this relationship is not well understood. OBJECTIVE: We used genome-wide association study (GWAS) data to identify shared genetic factors (pleiotropy) between MS and CVD risk factors. METHODS: Using summary statistics from a large, recent GWAS (total...
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