Article
Identification of novel oncogenes in oral cancer among elderly nonsmokers.
Clinical and experimental dental research - 1 Aug 2023
Inoue Hitoshi, Hirasaki Masataka, Kogashiwa Yasunao, Nakachi Yutaka, Kuba Kiyomi, Ebihara Yasuhiro, Nakahira Mitsuhiko, Yasuda Masanori, Okuda Akihiko, Sugasawa Masashi
Abstract excerpt
OBJECTIVES: In recent years, an increase in oral cancer among elderly nonsmokers has been noted. The aim of this study was to identify novel oncogenes in oral cancer in older nonsmokers. MATERIAL AND METHODS: Whole-exome sequencing (WES) data from 324 oral cancer patients were obtained from The Cancer Genome Atlas. Single nucleotide variants (SNVs) and insertions/deletions (INDELs) were extracted from the WES...
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