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Article

Integrated genomic analyses identify KDM1A's role in cell proliferation via modulating E2F signaling activity and associate with poor clinical outcome in oral cancer.

Cancer letters - 28 Oct 2015

Narayanan Sathiya Pandi, Singh Smriti, Gupta Amit, Yadav Sandhya, Singh Shree Ram, Shukla Sanjeev

Abstract excerpt

The histone demethylase KDM1A specifically demethylates lysine residues and its deregulation has been implicated in the initiation and progression of various cancers. However, KDM1A's molecular role and its pathological consequences, and prognostic significance in oral cancer remain less understood. In the present study, we sought to investigate the expression of KDM1A and its downstream role in oral cancer...

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Share to E2F1 Transcription Factor
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26225839
DOI: 10.1016/j.canlet.2015.07.022
PMCID: PMC7751892

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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