Whole-exome sequencing identifies MST1R as a genetic susceptibility gene in nasopharyngeal carcinoma.

doi:10.1073/pnas.1523436113

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Whole-exome sequencing identifies MST1R as a genetic susceptibility gene in nasopharyngeal carcinoma.

Proceedings of the National Academy of Sciences of the United States of America - 22 Mar 2016

Dai Wei, Zheng Hong, Cheung Arthur Kwok Leung, Tang Clara Sze-man, Ko Josephine Mun Yee, Wong Bonnie Wing Yan, Leong Merrin Man Long, Sham Pak Chung, Cheung Florence, Kwong Dora Lai-Wan, Ngan Roger Kai Cheong, Ng Wai Tong, Yau Chun Chung, Pan Jianji, Peng Xun, Tung Stewart, Zhang Zengfeng, Ji Mingfang, Chiang Alan Kwok-Shing, Lee Anne Wing-Mui, Lee Victor Ho-Fun, Lam Ka-On, Au Kwok Hung, Cheng Hoi Ching, Yiu Harry Ho-Yin, Lung Maria Li

Abstract excerpt

Multiple factors, including host genetics, environmental factors, and Epstein-Barr virus (EBV) infection, contribute to nasopharyngeal carcinoma (NPC) development. To identify genetic susceptibility genes for NPC, a whole-exome sequencing (WES) study was performed in 161 NPC cases and 895 controls of Southern Chinese descent. The gene-based burden test discovered an association between macrophage-stimulating 1...

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PMID: 26951679
DOI: 10.1073/pnas.1523436113
PMCID: PMC4812767

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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