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Oral cancer driver gene mutations in oral potentially malignant disorders: clinical significance and diagnostic implications

13 Feb 2025

Abstract excerpt

Oral potentially malignant disorders (OPMDs), such as oral lichen planus (OLP) and oral leukoplakia (OLK), are clinical conditions associated with the risk of developing oral squamous cell carcinoma; however, no standardized treatment guidelines exist. Mutations in specific genes, known as oral cancer driver gene mutations (ODGMs), are responsible for carcinogenesis. We aimed to analyze the ODGMs in OPMDs and...

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PMID: 39946003
DOI: 10.1007/s12672-025-01923-7

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