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Article

Loss of Human Leukocyte Antigen and Immune Escape in Head and Neck Cancer

30 May 2023

Abstract excerpt

OBJECTIVES/HYPOTHESIS: Cancer cells evade recognition by the immune system to survive. Head and neck squamous cell carcinoma (HNSCC) is characterized by high levels of immune infiltration and mutation-associated neoantigens; therefore, immune evasion is likely to be an important mechanism in HNSCC tumorigenesis and progression. A commonly employed mechanism of immune evasion is downregulation of human leukocyte...

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PMID: 37249223
DOI: 10.1002/lary.30761

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