Article

Long-term expanding human airway organoids for disease modelling

2018-05-09

Abstract excerpt

Organoids are self-organizing 3D structures grown from stem cells that recapitulate essential aspects of organ structure and function. Here we describe a method to establish long-term-expanding human airway organoids from broncho-alveolar biopsies or lavage material. The pseudostratified airway organoid epithelium consists of basal cells, functional multi-ciliated cells, mucus-producing goblet cells, and CC10-secr...

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Literature Corpus work: d1bbc089-f835-5182-9730-525e76a967d4
DOI: 10.1101/318444

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