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Article

The countdown to type 1 diabetes: when, how and why does the clock start?

Diabetologia - 1 Jul 2023

Ziegler Anette-Gabriele

Abstract excerpt

'The clock to type 1 diabetes has started when islet antibodies are first detected', commented George Eisenbarth with regard to the pathogenesis of type 1 diabetes. This review focuses on 'starting the clock', i.e. the initiation of pre-symptomatic islet autoimmunity/the first appearance of islet autoantibodies. In particular, this review addresses why susceptibility to developing islet autoimmunity is greatest...

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Share to Diabetes Mellitus, Type 1

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Insulin-Secreting Cells

Share to Islets of Langerhans

Source

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Identifiers

PMID: 37231274
DOI: 10.1007/s00125-023-05927-2
PMCID: PMC10212739

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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