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Article

The environment and the origins of islet autoimmunity and Type 1 diabetes.

Diabetic medicine : a journal of the British Diabetic Association - 1 Feb 2013

Eringsmark Regnéll S, Lernmark A

Abstract excerpt

Type 1 diabetes involves the specific destruction of the pancreatic islet β-cells, eventually resulting in a complete dependency of exogenous insulin. The clinical onset of diabetes is preceded by the appearance of autoantibodies against β-cell antigens. The human leukocyte antigen (HLA) region is the single most important genetic determinant of Type 1 diabetes susceptibility, yet variability in the HLA region...

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Share to Autoantibodies
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23252770
DOI: 10.1111/dme.12099
PMCID: PMC3552102

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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