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Article

Energy homeostasis genes modify the association between serum concentrations of IGF-1 and IGFBP-3 and breast cancer risk.

Scientific reports - 3 Feb 2022

Rodríguez-Valentín Rocío, Torres-Mejía Gabriela, Martínez-Matsushita Louis, Angeles-Llerenas Angélica, Gómez-Flores-Ramos Liliana, Wolff Roger K, Baumgartner Kathy B, Hines Lisa M, Ziv Elad, Flores-Luna Lourdes, Sánchez-Zamorano Luisa Ma, Ortiz-Panozo Eduardo, Slattery Martha L

Abstract excerpt

Breast cancer is a multifactorial disease in which the interplay among multiple risk factors remains unclear. Energy homeostasis genes play an important role in carcinogenesis and their interactions with the serum concentrations of IGF-1 and IGFBP-3 on the risk of breast cancer have not yet been investigated. The aim of this study was to assess the modifying effect of the genetic variation in some energy...

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Identifiers

PMID: 35115550
DOI: 10.1038/s41598-022-05496-1
PMCID: PMC8813998

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