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Genomic landscape and its prognostic significance in stage III colorectal cancer: JCOG1506A1, an ancillary of JCOG0910.

Cancer science - 1 Aug 2023

Shida Dai, Kuchiba Aya, Shibata Tatsuhiro, Hamaguchi Tetsuya, Yamasaki Satoshi, Ito Masaaki, Kobatake Takaya, Tonooka Toru, Masaki Tadahiko, Shiozawa Manabu, Takii Yasumasa, Uetake Hiroyuki, Okamura Shu, Ojima Hitoshi, Kazama Shinsuke, Takeyama Hiroshi, Kanato Keisuke, Shimada Yasuhiro, Murakami Yoshinori, Kanemitsu Yukihide

Abstract excerpt

Large-scale genomic sequencing of colorectal cancers has been reported mainly for Western populations. Differences by stage and ethnicity in the genomic landscape and their prognostic impact remain poorly understood. We investigated 534 Japanese stage III colorectal cancer samples from the Phase III trial, JCOG0910. Targeted-capture sequencing of 171 potentially colorectal cancer-associated genes was performed,...

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PMID: 37189003
DOI: 10.1111/cas.15834
PMCID: PMC10394152

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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