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Article

Genomic alterations associated with early-stage disease and early recurrence in patients with colorectal cancer.

The oncologist - 6 Feb 2025

Pappas Leontios, Quintanilha Julia C F, Huang Richard S P, Parikh Aparna R

Abstract excerpt

BACKGROUND: The molecular characterization of early-stage (1-3) colorectal cancer (CRC) remains incomplete, as opposed to metastatic disease, where comprehensive genomic profiling (CGP) is routinely performed. This study aimed to characterize the genomics of stages 1-3 versus IV CRC, and the genomics of patients recurring within 1 year of diagnosis. PATIENTS AND METHODS: Patients from a de-identified CRC...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39531357
DOI: 10.1093/oncolo/oyae269
PMCID: PMC11883158

Genes

MSH6
RNF43
BRAF
BRCA1
MLH1
MSH2

Variants

Provenance

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