Article
A prognostic mutation panel for predicting cancer recurrence in stages II and III colorectal cancer.
Journal of surgical oncology - 1 Dec 2017
Sho Shonan, Court Colin M, Winograd Paul, Russell Marcia M, Tomlinson James S
Abstract excerpt
BACKGROUND AND OBJECTIVES: Approximately 20-40% of stage II/III colorectal cancer (CRC) patients develop relapse. Clinicopathological factors alone are limited in detecting these patients, resulting in potential under/over-treatment. We sought to identify a prognostic tumor mutational profile that could predict CRC recurrence. METHODS: Whole-exome sequencing data were obtained for 207 patients with stage II/III...
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