Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of MYH9 as a key regulator for synoviocyte migration and invasion through secretome profiling

15 May 2023

Abstract excerpt

OBJECTIVES: 'Invasive pannus' is a pathological hallmark of rheumatoid arthritis (RA). This study aimed to investigate secretome profile of synovial fibroblasts of patients with RA (RA-FLSs), a major cell type comprising the invasive pannus. METHODS: Secreted proteins from RA-FLSs were first identified using liquid chromatography-tandem mass spectrometry analysis. Ultrasonography was performed for affected joints...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Share to Rheumatoid Arthritis Research and Therapies
Share to Spondyloarthritis Studies and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37188496
DOI: 10.1136/ard-2022-223625

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of MYH9 as a key regulator for synoviocyte migration and invasion through secretome profilingPMID 37188496Read ↗

Fibroblast-like synoviocytes in rheumatoid arthritis: Surface markers and phenotypes.Semantic proximity Read ↗

New Druggable Targets for Rheumatoid Arthritis Based on Insights From Synovial BiologySemantic proximity Read ↗

Identification of key regulators for the migration and invasion of rheumatoid synoviocytes through a systems approachSemantic proximity Read ↗

RNA-seq analysis of synovial fibroblasts brings new insights into rheumatoid arthritisSemantic proximity Read ↗

GALNT1 drives aggressive phenotypes of rheumatoid synoviocytes via NEK9 O-glycosylation.Semantic proximity Read ↗

Integrative Omics Analysis of Rheumatoid Arthritis Identifies Non-Obvious Therapeutic TargetsSemantic proximity Read ↗

Fibroblast-like synoviocytes: key effector cells in rheumatoid arthritis.Semantic proximity Read ↗

Targeting pathogenic fibroblast-like synoviocyte subsets in rheumatoid arthritisSemantic proximity Read ↗

Comprehensive epigenetic landscape of rheumatoid arthritis fibroblast-like synoviocytesSemantic proximity Read ↗

Type-1 interferon-driven innate and <i>GZMK</i> + CD8 T cell activation precedes subclinical joint inflammation when rheumatoid arthritis is imminentSemantic proximity Read ↗

CD39+CD55− Fb Subset Exhibits Myofibroblast-Like Phenotype and Is Associated with Pain in Osteoarthritis of the KneeSemantic proximity Read ↗

The Tumor-Like Phenotype of Rheumatoid Synovium: Molecular Profiling and Prospects for Precision Medicine.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.