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Article

KIF1C and new Huntingtin-interacting protein 1 binding proteins regulate rheumatoid arthritis fibroblast-like synoviocytes' phenotypes.

Frontiers in immunology - 1 Jan 2024

Laragione Teresina, Harris Carolyn, Gulko Percio S

Abstract excerpt

Background: Huntingtin-interacting protein-1 (HIP1) is a new arthritis severity gene implicated in the regulation of the invasive properties of rheumatoid arthritis (RA) fibroblast-like synoviocytes (FLS). These invasive properties of FLS strongly correlate with radiographic and histology damage in patients with RA and rodent models of arthritis. While HIP1 has several intracellular functions, little is known...

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Identifiers

PMID: 38726004
DOI: 10.3389/fimmu.2024.1323410
PMCID: PMC11079228

Genes

HIP1
KIF1C
COPE
YWHAG
YWHAH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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