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The Role of NAD+, SIRTs Interactions in Stimulating and Counteracting Carcinogenesis

27 Apr 2023

Abstract excerpt

The World Health Organization has identified oncological diseases as one of the most serious health concerns of the current century. Current research on oncogenesis is focused on the molecular mechanisms of energy-biochemical reprogramming in cancer cell metabolism, including processes contributing to the Warburg effect and the pro-oncogenic and anti-oncogenic roles of sirtuins (SIRTs) and poly-(ADP-ribose)...

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PMID: 37175631
DOI: 10.3390/ijms24097925

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