Article
Evaluation of myopia-associated genes in a Han Chinese population with high myopia.
Ophthalmic genetics - 1 Aug 2023
Liu Zhenzhen, An Guangqi, Huo Yadan, Xu Youmei, Zhou Pengyi, Xie Kunpeng, Zhu Haiyan, Jin Bo, Du Liping, Jin Xuemin
Abstract excerpt
BACKGROUND: High myopia is a leading cause of blindness worldwide. However, the exact etiology and mechanism of high myopia remain unclear. Previous genome-wide association study has demonstrated that nine single nucleotide polymorphisms (SNPs) in East and Southeast Asian populations were associated with high myopia and proved that the nervous system was involved in the pathogenesis of high myopia. The present...
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