Article
Genetic variants at 13q12.12 are associated with high myopia in the Han Chinese population.
American journal of human genetics - 10 Jun 2011
Shi Yi, Qu Jia, Zhang Dingding, Zhao Peiquan, Zhang Qingjiong, Tam Pancy Oi Sin, Sun Liangdan, Zuo Xianbo, Zhou Xiangtian, Xiao Xueshan, Hu Jianbin, Li Yuanfeng, Cai Li, Liu Xiaoqi, Lu Fang, Liao Shihuang, Chen Bin, He Fei, Gong Bo, Lin He, Ma Shi, Cheng Jing, Zhang Jie, Chen Yiye, Zhao Fuxin, Yang Xian, Chen Yuhong, Yang Charles, Lam Dennis Shun Chiu, Li Xi, Shi Fanjun, Wu Zhengzheng, Lin Ying, Yang Jiyun, Li Shiqiang, Ren Yunqing, Xue Anquan, Fan Yingchuan, Li Dean, Pang Chi Pui, Zhang Xuejun, Yang Zhenglin
Abstract excerpt
High myopia, which is extremely prevalent in the Chinese population, is one of the leading causes of blindness in the world. Genetic factors play a critical role in the development of the condition. To identify the genetic variants associated with high myopia in the Han Chinese, we conducted a genome-wide association study (GWAS) of 493,947 SNPs in 1088 individuals (419 cases and 669 controls) from a Han Chinese...
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