Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A genome-wide association analysis identified a novel susceptible locus for pathological myopia at 11q24.1.

PLoS genetics - 1 Sept 2009

Nakanishi Hideo, Yamada Ryo, Gotoh Norimoto, Hayashi Hisako, Yamashiro Kenji, Shimada Noriaki, Ohno-Matsui Kyoko, Mochizuki Manabu, Saito Masaaki, Iida Tomohiro, Matsuo Keitaro, Tajima Kazuo, Yoshimura Nagahisa, Matsuda Fumihiko

Abstract excerpt

Myopia is one of the most common ocular disorders worldwide. Pathological myopia, also called high myopia, comprises 1% to 5% of the general population and is one of the leading causes of legal blindness in developed countries. To identify genetic determinants associated with pathological myopia in Japanese, we conducted a genome-wide association study, analyzing 411,777 SNPs with 830 cases and 1,911 general...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes, Human, Pair 11
Share to Gene Expression Regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome, Human

Share to HeLa Cells

Share to Linkage Disequilibrium

Share to Myopia, Degenerative

Share to Retina

Source

Open in PubMed Open full text

Identifiers

PMID: 19779542
DOI: 10.1371/journal.pgen.1000660
PMCID: PMC2735651

Genes

BLID

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A genome-wide association analysis identified a novel susceptible locus for pathological myopia at 11q24.1.PMID 19779542Read ↗

Genetic variants at 13q12.12 are associated with high myopia in the Han Chinese population.Semantic proximity Read ↗

A genome-wide meta-analysis identifies two novel loci associated with high myopia in the Han Chinese population.Semantic proximity Read ↗

Myopia Genetics-The Asia-Pacific Perspective.Semantic proximity Read ↗

Molecular Genetics of Human Myopia: An UpdateSemantic proximity Read ↗

Evaluation of 12 myopia-associated genes in Chinese patients with high myopia.Semantic proximity Read ↗

A new locus for autosomal dominant high myopia maps to 4q22-q27 between D4S1578 and D4S1612.Semantic proximity Read ↗

Polymorphism in the 11q24.1 genomic region is associated with myopia: a comprehensive genetic study in Chinese and Japanese populations.Semantic proximity Read ↗

Genome-Wide Association Study in Asians Identifies Novel Loci for High Myopia and Highlights a Nervous System Role in Its Pathogenesis.Semantic proximity Read ↗

Myopia Genetics and HereditySemantic proximity Read ↗

Comprehensive replication of the relationship between myopia-related genes and refractive errors in a large Japanese cohort.Semantic proximity Read ↗

Association of 10 Genetic Variations and 10 Environmental Factors with Myopia of Different Severities in Different Age Groups of People in Northeast China.Semantic proximity Read ↗

Replication study of significant single nucleotide polymorphisms associated with myopia from two genome-wide association studies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.