Article

Whole-exome sequencing screening for candidate genes and potential pathogenic variants associated with early-onset high myopia in 47 Chinese families

2025-01-14

Abstract excerpt

<title>Abstract</title> <p>Early-onset high myopia (eoHM) occurs before school age and is an ideal model for monogenic studies of high myopia due to minimal environmental influence. This study screened for genes and variants associated with eoHM in 47 unrelated Chinese patients with eoHM. Protein-protein interaction (PPI) network analysis was conducted to detect interactions among candidate genes, and protein-pro...

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Literature Corpus work: 40b9fcb4-7045-5fb5-877d-4824f7676fa7
DOI: 10.21203/rs.3.rs-5761253/v1

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