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Article

Evaluation of 12 myopia-associated genes in Chinese patients with high myopia.

Investigative ophthalmology & visual science - 13 Jan 2015

Li Jiali, Jiang Dan, Xiao Xueshan, Li Shiqiang, Jia Xiaoyun, Sun Wenmin, Guo Xiangming, Zhang Qingjiong

Abstract excerpt

PURPOSE: Two recent large-scale genome-wide association studies identified significant associations between myopia and single nucleotide polymorphisms (SNPs) near the PRSS56, BMP3, KCNQ5, LAMA2, TOX, TJP2, RDH5, ZIC2, RASGRF1, GJD2, RBFOX1, and SHISA6 genes. Our study is to examine whether rare variants in these genes contribute to high myopia. METHODS: Whole-exome sequencing was performed on samples of 298...

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Source

Identifiers

PMID: 25587058
DOI: 10.1167/iovs.14-14880

Genes

GJD2
BMP3
KCNQ5
LAMA2
PRSS56
RASGRF1
RBFOX1
RDH5
SHISA6
TJP2
TOX
ZIC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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