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Mutation Screening of ARR3, CACNA1F, P4HA2, TRPM1, COL2A1, COL11A1 and PAX6 in a Chinese Cohort of 37 Patients with Early-Onset High Myopia.

Genes - 29 Mar 2026

Liu Xue, Chu Huihui, Sun Yaru, Zhao Haixia, Yu Jifeng

Abstract excerpt

Background/Objectives: Early-onset high myopia (eoHM), defined as high myopia manifesting before 10 years of age, is largely attributed to genetic defects. This study aimed to investigate the genetic underpinnings of eoHM in a cohort of Chinese patients. Methods: We recruited 64 Chinese patients with eoHM. Comprehensive clinical evaluations were performed, and whole exome sequencing (WES) was conducted to...

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Source

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Identifiers

PMID: 42074509
DOI: 10.3390/genes17040391
PMCID: PMC13116366

Genes

ARR3
CACNA1F
COL11A1
COL2A1
P4HA2
PAX6
TRPM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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Mutation Screening of ARR3, CACNA1F, P4HA2, TRPM1, COL2A1, COL11A1 and PAX6 in a Chinese Cohort of 37 Patients with Early-Onset High Myopia.PMID 42074509Read ↗

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