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Article

KRAS, MYC, and ARF6: inseparable relationships cooperatively promote cancer malignancy and immune evasion.

Cell communication and signaling : CCS - 8 May 2023

Sabe Hisataka

Abstract excerpt

Mutations in the KRAS gene and overexpression of protein products of the MYC and ARF6 genes occur frequently in cancer. Here, the inseparable relationships and cooperation of the protein products of these three genes in cancer malignancy and immune evasion are discussed. mRNAs encoded by these genes share the common feature of a G-quadruplex structure, which directs them to be robustly expressed when cellular...

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Share to ADP-Ribosylation Factor 6
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Pancreatic Neoplasms

Share to Proto-Oncogene Proteins c-myc

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Source

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Identifiers

PMID: 37158894
DOI: 10.1186/s12964-023-01130-3
PMCID: PMC10165578

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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