Article

STAT3 and STAT5 Activation in Solid Cancers

2019-08-05

Abstract excerpt

The Signal Transducer and Activator of Transcription (STAT)3 and 5 are activated by many cytokine receptors to regulate specific gene expression and mitochondrial functions. Their role in cancer is largely context dependent as they can both act as oncogenes and tumor suppressors. We review here the role of STAT3/5 activation in solid cancers and summarize their association to survival in cancer patients. The molec...

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Literature Corpus work: 7e4cc88d-9f45-50db-8fa6-dafa25bfe66e
DOI: 10.20944/preprints201908.0038.v1

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