Genetic architecture of the inflammatory bowel diseases across East Asian and European ancestries.

doi:10.1038/s41588-023-01384-0

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Article

Genetic architecture of the inflammatory bowel diseases across East Asian and European ancestries.

Nature genetics - 1 May 2023

Liu Zhanju, Liu Ruize, Gao Han, Jung Seulgi, Gao Xiang, Sun Ruicong, Liu Xiaoming, Kim Yongjae, Lee Ho-Su, Kawai Yosuke, Nagasaki Masao, Umeno Junji, Tokunaga Katsushi, Kinouchi Yoshitaka, Masamune Atsushi, Shi Wenzhao, Shen Chengguo, Guo Zhenglin, Yuan Kai, Zhu Shu, Li Dalin, Liu Jianjun, Ge Tian, Cho Judy, Daly Mark J, McGovern Dermot P B, Ye Byong Duk, Song Kyuyoung, Kakuta Yoichi, Li Mingsong, Huang Hailiang

Abstract excerpt

Inflammatory bowel diseases (IBDs) are chronic disorders of the gastrointestinal tract with the following two subtypes: Crohn's disease (CD) and ulcerative colitis (UC). To date, most IBD genetic associations were derived from individuals of European (EUR) ancestries. Here we report the largest IBD study of individuals of East Asian (EAS) ancestries, including 14,393 cases and 15,456 controls. We found 80 IBD...

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Identifiers

PMID: 37156999
DOI: 10.1038/s41588-023-01384-0
PMCID: PMC10290755

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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