Genetic architecture differences between pediatric and adult-onset inflammatory bowel diseases in the Polish population.

doi:10.1038/srep39831

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Genetic architecture differences between pediatric and adult-onset inflammatory bowel diseases in the Polish population.

Scientific reports - 23 Dec 2016

Ostrowski Jerzy, Paziewska Agnieszka, Lazowska Izabella, Ambrozkiewicz Filip, Goryca Krzysztof, Kulecka Maria, Rawa Tomasz, Karczmarski Jakub, Dabrowska Michalina, Zeber-Lubecka Natalia, Tomecki Roman, Kluska Anna, Balabas Aneta, Piatkowska Magdalena, Paczkowska Katarzyna, Kierkus Jaroslaw, Socha Piotr, Lodyga Michal, Rydzewska Grazyna, Klopocka Maria, Mierzwa Grazyna, Iwanczak Barbara, Krzesiek Elzbieta, Bak-Drabik Katarzyna, Walkowiak Jaroslaw, Klincewicz Beata, Radwan Piotr, Grzybowska-Chlebowczyk Urszula, Landowski Piotr, Jankowska Agnieszka, Korczowski Bartosz, Starzynska Teresa, Albrecht Piotr, Mikula Michal

Abstract excerpt

Most inflammatory bowel diseases (IBDs) are classic complex disorders represented by common alleles. Here we aimed to define the genetic architecture of pediatric and adult-onset IBDs for the Polish population. A total of 1495 patients were recruited, including 761 patients with Crohn's disease (CD; 424 pediatric), 734 patients with ulcerative colitis (UC; 390 pediatric), and 934 healthy controls. Allelotyping...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Aging

Share to Child

Share to Child, Preschool

Share to Genome-Wide Association Study

Share to Inflammatory Bowel Diseases

Share to Poland

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 28008999
DOI: 10.1038/srep39831
PMCID: PMC5180213

Genes

BRD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic architecture differences between pediatric and adult-onset inflammatory bowel diseases in the Polish population.PMID 28008999Read ↗

The genetic architecture of inflammatory bowel disease: past, present and future.Semantic proximity Read ↗

Dissecting Allele Architecture of Early Onset IBD Using High-Density Genotyping.Semantic proximity Read ↗

Inflammatory Bowel Disease: Genetics, Epigenetics, and PathogenesisSemantic proximity Read ↗

Genetic variants and pathways implicated in a pediatric inflammatory bowel disease cohortSemantic proximity Read ↗

An Overview of Inflammatory Bowel Disease: General Consideration and Genetic Screening Approach in Diagnosis of Early Onset SubsetsSemantic proximity Read ↗

Pediatric inflammatory bowel disease: clinical and molecular genetics.Semantic proximity Read ↗

The role of monogenic disease in children with very early onset inflammatory bowel disease.Semantic proximity Read ↗

Role of genetics in pediatric inflammatory bowel disease.Semantic proximity Read ↗

Clinical Genomics for the Diagnosis of Monogenic Forms of Inflammatory Bowel DiseaseSemantic proximity Read ↗

Prevalence and Clinical Features of Inflammatory Bowel Diseases Associated With Monogenic Variants, Identified by Whole-Exome Sequencing in 1000 Children at a Single Center.Semantic proximity Read ↗

Genetic Sequencing of Pediatric Patients Identifies Mutations in Monogenic Inflammatory Bowel Disease Genes that Translate to Distinct Clinical Phenotypes.Semantic proximity Read ↗

Genetic architecture of the inflammatory bowel diseases across East Asian and European ancestries.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.