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Article

p53 Antibodies as a Diagnostic Marker for Cancer: A Meta-Analysis.

Molecules (Basel, Switzerland) - 14 Oct 2021

Sobhani Navid, Roviello Giandomenico, D'Angelo Alberto, Roudi Raheleh, Neeli Praveen Kumar, Generali Daniele

Abstract excerpt

Importance: The protein p53 is an unequivocal tumor suppressor that is altered in half of all cancers. The immune system produces systemic p53 autoantibodies (p53 Abs) in many cancer patients. Objective: This systemic review and meta-analysis focuses on the prognostic value of p53 Abs expressed in the serum of patients with solid tumors. Data Sources: All the clinical investigations were searched on PubMed from...

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Identifiers

PMID: 34684792
DOI: 10.3390/molecules26206215
PMCID: PMC8541220

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