Article
The clinical and molecular spectrum of ETV6 mutated myeloid neoplasms.
British journal of haematology - 1 Jul 2023
Gurney Mark, Chekkaf Ismahene, Baranwal Anmol, Basmaci Rami, Katamesh Bahga, Greipp Patricia, Foran James M, Badar Talha, Mangaonkar Abhishek A, Begna Kebede H, Gangat Naseema, Patnaik Mrinal M, Litzow Mark R, Shah Mithun V, Viswanatha David S, He Rong, Alkhateeb Hassan B, Al-Kali Aref
Abstract excerpt
ETV6 mutations are rare but recurrent somatic events in myeloid neoplasms and are negatively prognostic in myelodysplastic syndrome. We set out to examine the clinical and molecular characteristics of patients undergoing investigation for myeloid neoplasms, found to have deleterious ETV6 mutations. ETV6 mutations occurred in 33 of 5793 (0.6%) cases investigated and predominantly in high-risk disease entities...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.