ETV6 and signaling gene mutations are associated with secondary transformation of myelodysplastic syndromes to chronic myelomonocytic leukemia

Abstract excerpt

To the editor: The genetic determinants that govern the phenotype associated with chronic myelomonocytic leukemia (CMML) and myelodysplastic syndromes (MDS) are unknown. Many recurrent mutations occur in both diseases, suggesting that the presence or absence of a solitary mutation is insufficient

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