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Article

Assessment of HLA-DPB1 genetic variation using an HLA-DP tool and its implications in clinical transplantation.

Blood advances - 12 Sept 2023

Sajulga Ray, Bolon Yung-Tsi, Maiers Martin J, Petersdorf Effie W

Abstract excerpt

HLA-DP is a classic transplantation antigen that mediates alloreactivity through T-cell epitope (TCE) diversity and expression levels. A current challenge is to integrate these functional features into the prospective selection of unrelated donor candidates for transplantation. Genetically, HLA-DPB1 exon 2 defines the permissive and nonpermissive TCE groups, and exons 2 and 3 (in linkage with rs9277534) indicate...

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Identifiers

PMID: 37126658
DOI: 10.1182/bloodadvances.2022009554
PMCID: PMC10469530

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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