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A Combined HLA Molecular Mismatch and Expression Analysis for Evaluating HLA-DPB1 <i>de novo</i> Donor-Specific Antibody Risk in Pediatric Solid Organ Transplantation: Implications for Solid Organ & Hematopoietic Stem Cell Transplantation

2020-01-10

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> HLA molecular mismatch (MM) has been shown to be a risk factor for de novo donor-specific antibody ( dn DSA) development in solid organ transplantation (SOT). HLA expression differences have also been associated with adverse outcomes in hematopoietic cell transplantation. We sought to study both MM and expression in assessing dn DSA risk. <h4>Methods</h4> One-hundred-and-three...

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Literature Corpus work
6554459c-afaa-5fa5-a44e-5b77944cc44d
DOI
10.1101/2020.01.06.20016709
Open publication

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A Combined HLA Molecular Mismatch and Expression Analysis for Evaluating HLA-DPB1 <i>de novo</i> Donor-Specific Antibody Risk in Pediatric Solid Organ Transplantation: Implications for Solid Organ & Hematopoietic Stem Cell TransplantationDOI 10.1101/2020.01.06.20016709
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