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Article

Mutations in SARS-CoV-2 variant nsp6 enhance type-I interferon antagonism.

Emerging microbes & infections - 1 Dec 2023

Bills Cody J, Xia Hongjie, Chen John Yun-Chung, Yeung Jason, Kalveram Birte K, Walker David, Xie Xuping, Shi Pei-Yong

Abstract excerpt

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to evolve after its emergence. Given its importance in viral infection and vaccine development, mutations in the viral Spike gene have been studied extensively; however, the impact of mutations outside the Spike gene are poorly understood. Here, we report that a triple deletion (ΔSGF or ΔLSG) in nonstructural protein 6 (nsp6) independently...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 37114433
DOI: 10.1080/22221751.2023.2209208
PMCID: PMC10184609

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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