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Article

Manipulation of innate immune signaling pathways by SARS-CoV-2 non-structural proteins

21 Nov 2022

Abstract excerpt

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of the current coronavirus disease 2019 (COVID-19) pandemic, induces an unbalanced immune response in the host. For instance, the production of type I interferon (IFN) and the response to it, which act as a front-line defense against virus invasion, are inhibited during SARS-CoV-2 infection. In addition, tumor necrosis factor alpha...

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PMID: 36478862
DOI: 10.3389/fmicb.2022.1027015

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