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Article

Co-mutation of ASXL1 and SF3B1 Predicts Poorer Overall Survival Than Isolated ASXL1 or SF3B1 Mutations.

In vivo (Athens, Greece) - 1 Jan 2000

Song Jinming, Moscinski Lynn, Yang Ethan, Shao Haipeng, Hussaini Mohammad, Zhang Hailing

Abstract excerpt

BACKGROUND/AIM: Mutations in the ASXL transcriptional regulator 1 (ASXL1) and splicing factor 3b subunit 1(SF3B1) genes are commonly observed in myeloid neoplasms and are independent predicative factors for overall survival (OS). Only a few contradictory reports exist on the clinical significance of concurrent ASXL1 and SF3B1 mutations. Previous studies also did not exclude patients with mutations of other genes,...

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Identifiers

PMID: 37103105
DOI: 10.21873/invivo.13172
PMCID: PMC10188047

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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