Article
Pathologic Spectrum and Molecular Landscape of Myeloid Disorders Harboring SF3B1 Mutations.
American journal of clinical pathology - 8 Sept 2021
Venable Elise R, Chen Dong, Chen Constance P, Bessonen Kurt R, Nguyen Phuong L, Oliveira Jennifer L, Reichard Kaaren K, Hoyer James D, Althoff Simon D, Roh Dana J, Miller Mechelle A, Begna Kebede, Patnaik Mrinal M, Litzow Mark R, Al-Kali Aref, Viswanatha David S, He Rong
Abstract excerpt
OBJECTIVES: SF3B1 mutations are the most common mutations in myelodysplastic syndromes (MDS). The International Working Group for the Prognosis of MDS (IWG-PM) recently proposed SF3B1-mutant MDS (SF3B1-mut-MDS) as a distinct disease subtype. We evaluated the spectrum and molecular landscape of SF3B1-mutated myeloid disorders and assessed the prognostication in MDS harboring SF3B1 mutations (MDS-SF3B1). METHODS:...
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