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Article

Clinical implications of myeloid malignancy‑related somatic mutations in aplastic anemia.

Clinical and experimental medicine - 1 Dec 2023

Liu Lingling, Zhang Danfeng, Fu Qiuhao, Wang Jingdi, Yu Jifeng, Chen Dandan, Wang Fang, Guo Rong, Xie Xinsheng, Jiang Zhongxing, Li Yingmei

Abstract excerpt

Aplastic anemia (AA) is a potentially fatal bone marrow failure syndrome characterized by a paucity of hematopoietic stem cells and progenitor cells with varying degrees of cytopenia and fatty infiltration of the bone marrow space. Recent advances in genomics have uncovered a link between somatic mutations and myeloid cancer in AA patients. At present, the impact of these mutations on AA patients remains...

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Identifiers

PMID: 37087521
DOI: 10.1007/s10238-023-01067-4
PMCID: PMC10725342

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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