Article
Implications of Mutation Profiling in Myeloid Malignancies-PART 1: Myelodysplastic Syndromes and Acute Myeloid Leukemia.
Oncology (Williston Park, N.Y.) - 15 Apr 2018
Tremblay Douglas, Sokol Kelsey, Bhalla Sheena, Rampal Raajit, Mascarenhas John O
Abstract excerpt
The advent of high-throughput gene sequencing has revolutionized our understanding of the genetic mutations that drive myeloid malignancies. While these mutations are of interest pathobiologically, they are increasingly being recognized as clinically meaningful in providing diagnostic, prognostic, and therapeutic information to guide patient care. In this first part of our two-part review, we introduce mutation...
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